DeepVigilace Logo
The DeepVigilace Project
DeepVigilace
Road to machine-assisted pharmacovigilance

About DeepVigilace

Drug safety is the main goal of pharmacovigilance, yet the field is plagued by the constraints of textual information processing. In this project, we adapted contrastive learning methods to create vector representations, i.e. embeddings, of adverse events, and trained a deep neural network classifier to determine the causal relation of drug–event pairs.

The aim of the project is to help further the cause of computer-assisted causality assessment for authorities and field experts in pharmacovigilance. Therefore, we provide open access to our framework as well as adverse event embeddings, ready for machine learning applications in research and development.

Article Image

Contrastive Learning of Adverse Events to Provide Effective and Interpretable Vector Representations for Machine-Assisted Pharmacovigilance

Read the article Download data (ZIP, 2.5 GB) View code on GitHub

Cite Us

MLA

Balogh, Olivér Márton, et al. "Contrastive Learning of Adverse Events to Provide Effective and Interpretable Vector Representations for Machine-Assisted Pharmacovigilance." bioRxiv (2025): 2025.06.04.657852. Print.

APA

Balogh, O. M., Pétervári, M., Csernák, Á. M., Puhl, E., Horváth, A., Ferdinandy, P., & Ágg, B. (2025). Contrastive learning of adverse events to provide effective and interpretable vector representations for machine-assisted pharmacovigilance. bioRxiv, 2025.2006.2004.657852. doi.org/10.1101/2025.06.04.657852

Explore our other projects

Post-transcriptional regulation

Mitigating off-target effects of small RNAs

Article
Protein–protein interactions (PPIs)

Community efforts to advance network-based PPI prediction

Article GitHub
Pharmacovigilance

Network-based analysis of individual case safety reports

Article vigilace.com
Protein–protein interactions (PPIs)

Generative adversarial model for link prediction in PPI networks

Article GitHub
Network Visualization

The EntOptLayout Cytoscape plug-in for efficient visualization of network modules

Article Plug-in
Post-transcriptional regulation

Analysis of microRNA-target interaction networks

Article miRNAtarget.com